123 | P a g e e-ISSN 2249 - 7749 Print ISSN 2249 – 7757 ANTIMICROBIAL AND PHARMACOLOGICAL EVALUATION OF NEWER SUBSTITUTED COUMARIN DERIVATIVES

A. Zechariah Jebakumar
Dept. of Research and Scientific studies, Prince Sultan Military college of Health Sciences, Dhahran-31932, Kingdom of Saudi Arabia.
Hassan S. Nondo
Dept. of Research and Scientific studies, Prince Sultan Military college of Health Sciences, Dhahran-31932, Kingdom of Saudi Arabia.
Siju K. George
Dept. of Research and Scientific studies, Prince Sultan Military college of Health Sciences, Dhahran-31932, Kingdom of Saudi Arabia.
G.Manoj
Dept of Pharmacology, C.L. Baid Metha College of Pharmacy, Thoraipakkam, Chennai - 600096, India

Antidiarrhoeal activity ,Randia uliginosa ,Traditional medicine ,Castor oil induced diarrhoea ,Enteropooling method ,

A series of substituted Coumarin derivatives (2a-j) have been screened in vitro for antibacterial, antifungal and in vivo, for their anti-inflammatory activity. Most of the compounds were found to be most potent antimicrobial and anti-inflammatory as compared with the reference drugs used.

4 , 3 , 2014