SCREENING OF IN VITRO ANTI-INFLAMMATORY ACTIVITY OF AQUEOUS EXTRACT OF LEAVES OF SHOREA ROBUSTA

A. Zechariah Jebakumar
Dept. of Research and Scientific studies, Prince Sultan Military college of Health Sciences, Dhahran-31932, Kingdom of Saudi Arabia.
Hassan S. Nondo
Dept. of Research and Scientific studies, Prince Sultan Military college of Health Sciences, Dhahran-31932, Kingdom of Saudi Arabia.
Siju K. George
Dept. of Research and Scientific studies, Prince Sultan Military college of Health Sciences, Dhahran-31932, Kingdom of Saudi Arabia.
G.Manoj
Dept of Pharmacology, C.L. Baid Metha College of Pharmacy, Thoraipakkam, Chennai - 600096, India

Antidiarrhoeal activity ,Randia uliginosa ,Traditional medicine ,Castor oil induced diarrhoea ,Enteropooling method ,

Present study is to investigate anti-inflammatory activity on the aqueous extract of Shorea robusta, in-vitro. As per phytochemical investigation the extract shows presence of flavanoids, tannins & saponins. The aqueous extract of Shorea robusta with a dose of 100, 200 & 500 μg/ml, was taken for the activity & compared with the standard Diclofenac doses of 20 & 40 μg/ml, in HRBC membrane stabilization model and same dose of extract was taken for activity & compared with Aspirin 200 μg/ml, using Heat induce haemolytic method. The extract of 500 μg/ml showed good result in both models.

3 , 2 , 2013