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In the present study, documented cutaneous adverse drug reactions (CADR) were assessed and analyzed for incidence, types of cutaneous reaction, drug classes, individual drug causing CADR, their management and outcome. To strengthen the association, CADR were also assessed for causality, using Naranjo’s scale. A total of 82 cases diagnosed as cutaneous adverse drug reactions in Dermatology department were enrolled during the study period of 6 months Results- Maximum number of CADR were due to analgesics (39%), antimicrobials ( 33%), antiepileptic drugs (13.41%) and steroids (12%) etc. Most of them (92%) were managed by withdrawal of drug. Naranjo’s scale classified 90% as probable, 9% as definite and 1% as possible ADR’s. Most of the ADR were of moderate severity. Fixed drug eruptions (51%) followed by maculopapular rashes (27%), drug induced urticaria (6%), Stevens - Johnson’s syndrome / Toxic epidermal necrolysis (3.64%) acute contact dermatitis (3.64%) etc were noted in most of the patients. Drugs responsible to cause such reactions were diclofenac, paracetamol, nimesulide, norfloxacin - tinidazole, fluconazole, isoniazid, phenytoin, stavudine, betamethasone cream etc. 89% patients cured by using oral antihistaminics, steroids, emollient cream, mometasone + fusidic acid cream etc while others (11%) improved. Cutaneous manifestations are commonly encountered in clinical practice as adverse reactions of drugs that are prescribed or self administered, Knowledge of CADR’s is must for physicians so that they can be prevented, diagnosed and reported.

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