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IJPSM JOURNAL
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Issn  2249-7579
e Issn  2249-7579
Publisher JOURNAL OF PHARMACEUTICAL BIOLOGY

SCREENING OF HEPATOPROTECTIVE ACTIVITY OF METHANOLIC EXTRACT OF ENTEROMORPHA LINZA (L.) J.AG. IN HARE ISLAND, THOOTHUKUDI, TAMIL NADU, INDIA

A. Zechariah Jebakumar
Dept. of Research and Scientific studies, Prince Sultan Military college of Health Sciences, Dhahran-31932, Kingdom of Saudi Arabia.
Hassan S. Nondo
Dept. of Research and Scientific studies, Prince Sultan Military college of Health Sciences, Dhahran-31932, Kingdom of Saudi Arabia.
Siju K. George
Dept. of Research and Scientific studies, Prince Sultan Military college of Health Sciences, Dhahran-31932, Kingdom of Saudi Arabia.
G.Manoj
Dept of Pharmacology, C.L. Baid Metha College of Pharmacy, Thoraipakkam, Chennai - 600096, India

Antidiarrhoeal activity ,Randia uliginosa ,Traditional medicine ,Castor oil induced diarrhoea ,Enteropooling method ,

Seaweeds have various valuable bioactive compounds of interest in the field of pharmaceutical and biomedical. In the present study, hepatoprotective activity of Enteromorpha linza (L.) J.Ag. collected from Hare Island, Thoothukudi in the south east coast of Tamil Nadu, India was screened. Dry powdered plant materials were subjected to methanolic extract at the dose of 200mg/kg and 400mg/kg body weight. Methanolic crude extract showed potential significant hepatoprotective activity in both doses. Among the two concentrations of methanolic extract studied, 200mg/kg methanolic extract was identified to show more active as compared to 400mg/kg methanolic extract. The results showed for the first time that Enteromorpha linza (L.) J.Ag. showed hepatoprotective activity, a property that could lead to the application in one of many useful health care

7 , 1 , 2017

1 - 5

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