HYPOLIPIDEMIC POTENTIAL OF ACTINIDIA DELICIOSA ON TRITON WR 1339 INDUCED HYPERLIPIDEMIA MALE ALBINO WISTAR RATS

A. Zechariah Jebakumar
Dept. of Research and Scientific studies, Prince Sultan Military college of Health Sciences, Dhahran-31932, Kingdom of Saudi Arabia.
Hassan S. Nondo
Dept. of Research and Scientific studies, Prince Sultan Military college of Health Sciences, Dhahran-31932, Kingdom of Saudi Arabia.
Siju K. George
Dept. of Research and Scientific studies, Prince Sultan Military college of Health Sciences, Dhahran-31932, Kingdom of Saudi Arabia.
G.Manoj
Dept of Pharmacology, C.L. Baid Metha College of Pharmacy, Thoraipakkam, Chennai - 600096, India

Antidiarrhoeal activity ,Randia uliginosa ,Traditional medicine ,Castor oil induced diarrhoea ,Enteropooling method ,

The aim of this study has been to investigate the possible hypolipidemic effect of Actinidia deliciosa Fruit extracts on triton (400 mg/kg b.w.) induced hyperlipidemia in Albino Wistar Rats. A comparison was made between the actions of Fruit (400 mg/kg b. w.) extracts of Actinidia deliciosa and a known hypolipidemic drug Atorvastatin (10 mg /kg b. w.). Parameters such as blood serum Total cholesterol, HDL, LDL, VLDL cholesterol, triglyceride levels and body weights of a ll groups of animals were estimated. Increase in the serum lipid profile with triton treatment was found to be significantly decreasing with test drugs and Atorvastatin. Administration of Actinidia deliciosa Fruit extracts significantly reduce both fat deposition and reduced in serum cholesterol and increased serum HDL levels in grains extracts Fruit (Juice) Extract groups when compare to their respective triton group. It indicates that Fruit extracts of Actinidia deliciosa has beneficial effect in preventing hyperlipidemia.

7 , 2 , 2017