Chenopodium album was reported to contain trypsin inhibitor activity 0.11-0.17 TIU/mg, total phenols 224.99-304.98 mgGAE/100g, simple phenols 72.50-101.007 mgGAE/100g and tannins 152.49- 203.91 mgGAE/100g, saponin 0.043-0.867 g/100g, phytic acid 238.3-268.33 mg/100g, phytate phosphorus 67.16-75.62 mg/100g, alkaloids 1-27-1.53 mg/100g, flavonoids 220.0-406.67 mg/100g, oxalates 394.19-477.08 mg/100g, oils, proteins , trace elements amd many other bioactive contents . It was reported that Chenopodium album exerted anti-inflammatory, analgesic, gastroprotective, hepatoprotective, anticancer, antioxidant, antimicrobial , anthelmintic, insecticidal and many other effects. The present review will highlight the chemical constituents and the pharmacological and therapeutic effects of Chenopodium album.