Edible vaccines may play a great role in limiting the infectious as well as non infectious diseases in future particularly in developing world. Owing to its low cost, easy-to-administer, easy-to-store, fail-safe and socioculturally readily acceptable vaccine delivery system, these vaccines are particularly suitable for developing countries. The technique for production of edible vaccines involves introduction of selected desired genes of immunogenic proteins from various pathogens into plants and animals and then inducing these altered organisms to manufacture the encoded proteins. Edible vaccines are targeted to provide mucosal as well as systemic immunity. The future of edible vaccines depends on acceptability for genetically modified foods. Successful implementation of edible vaccines relies on how well we overcome various technical obstacles, regulatory issues and non-scientific challenges.