Gastric ulcer is a very common global problem now days. Among various causes of gastric ulceration lesions caused by stress, alcohol consumption, H.pylori infection use of NSAIDs, Uneven food habits, Gastric irritants. Hyper secretion of gastric acid is a pathological condition, which occurs due to uncontrolled secretion of hydrochloric acid from the parietal cells of gastric mucosa through the proton pumping H+ K+ ATPase. The modern approach to control gastric ulcer is to inhibit gastric acid secretion, to promote gastro protection.